SubtiBank SubtiBank
ylyB [2019-08-01 09:54:22]
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ylyB [2019-08-01 09:54:22]

similar to pseudouridylate synthase
Locus
BSU_15460
Isoelectric point
5.43
Molecular weight
33.50 kDa
Protein length
303 aa Sequence Blast
Gene length
912 bp Sequence Blast
Function
RNA modification
Product
putative pseudouridylate synthase
Essential
no
E.C.
5.4.99.23
Synonyms
ylmL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → rRNA modification and maturation/ based on similarity

    • Gene

    Coordinates
    1,617,210 → 1,618,121

    The protein

    Catalyzed reaction/ biological activity

  • RNA uridine = RNA pseudouridine (according to Swiss-Prot)

    • Protein family

  • S4 RNA-binding domain superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)
  • pseudouridine synthase RluA family (with YjbO and YhcT, according to UniProt)

    • Paralogous protein(s)

  • YhcT, YjbO

    • Domains

  • S4 RNA-binding domain (aa 15 ... 93) (according to UniProt)

    • Structure

  • 1V9F (RluD from E. coli, 42% identical) PubMed

    • Expression and Regulation

    Operons

    Genes
    lspA-ylyB-pyrR
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE15460 (ΔylyB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AGCGGTTATATCAATTTGAT, downstream forward: _UP4_TGACAGAGGGTTTCTTTTCT
  • BKK15460 (ΔylyB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AGCGGTTATATCAATTTGAT, downstream forward: _UP4_TGACAGAGGGTTTCTTTTCT

    • References

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